Health related quality of life of women in TEACH, a randomised placebo controlled adjuvant trial of lapatinib in early stage Human Epidermal Growth Factor Receptor (HER2) overexpressing breast cancer.
Identifieur interne : 002D13 ( Main/Exploration ); précédent : 002D12; suivant : 002D14Health related quality of life of women in TEACH, a randomised placebo controlled adjuvant trial of lapatinib in early stage Human Epidermal Growth Factor Receptor (HER2) overexpressing breast cancer.
Auteurs : Frances M. Boyle [Australie] ; Ian E. Smith [Royaume-Uni] ; Joyce O'Shaughnessy [États-Unis] ; Bent Ejlertsen [Danemark] ; Aman U. Buzdar [États-Unis] ; Pierre Fumoleau [France] ; William Gradishar [États-Unis] ; Miguel Martin [Espagne] ; Beverly Moy [États-Unis] ; Martine Piccart-Gebhart [Belgique] ; Kathleen I. Pritchard [Canada] ; Deborah Lindquist [États-Unis] ; Mayur Amonkar [Royaume-Uni] ; Yingjie Huang [Royaume-Uni] ; Erica Rappold [Royaume-Uni] ; Lisa S. Williams [Royaume-Uni] ; Jing Wang-Silvanto [Royaume-Uni] ; Tomomi Kaneko [Royaume-Uni] ; Dianne M. Finkelstein [États-Unis] ; Paul E. Goss [États-Unis]Source :
- European journal of cancer (Oxford, England : 1990) [ 1879-0852 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Antinéoplasiques (usage thérapeutique), Enquêtes et questionnaires, Femelle, Humains, Qualité de vie, Quinazolines (usage thérapeutique), Récepteur ErbB-2 (biosynthèse), Survie sans rechute, Traitement médicamenteux adjuvant, Tumeurs du sein (anatomopathologie), Tumeurs du sein (enzymologie), Tumeurs du sein (traitement médicamenteux).
- MESH :
- anatomopathologie : Tumeurs du sein.
- biosynthèse : Récepteur ErbB-2.
- enzymologie : Tumeurs du sein.
- traitement médicamenteux : Tumeurs du sein.
- usage thérapeutique : Antinéoplasiques, Quinazolines.
- Adulte d'âge moyen, Enquêtes et questionnaires, Femelle, Humains, Qualité de vie, Survie sans rechute, Traitement médicamenteux adjuvant.
English descriptors
- KwdEn :
- Antineoplastic Agents (therapeutic use), Breast Neoplasms (drug therapy), Breast Neoplasms (enzymology), Breast Neoplasms (pathology), Chemotherapy, Adjuvant, Disease-Free Survival, Female, Humans, Middle Aged, Quality of Life, Quinazolines (therapeutic use), Receptor, ErbB-2 (biosynthesis), Surveys and Questionnaires.
- MESH :
- chemical , biosynthesis : Receptor, ErbB-2.
- chemical , therapeutic use : Antineoplastic Agents, Quinazolines.
- drug therapy : Breast Neoplasms.
- enzymology : Breast Neoplasms.
- pathology : Breast Neoplasms.
- Chemotherapy, Adjuvant, Disease-Free Survival, Female, Humans, Middle Aged, Quality of Life, Surveys and Questionnaires.
Abstract
To evaluate health related quality of life (HRQOL) in TEACH, a phase III randomized placebo controlled trial of 12 months of adjuvant lapatinib in HER2 positive (HER2+) early breast cancer which demonstrated marginal benefit in disease-free survival.
DOI: 10.1016/j.ejca.2015.02.005
PubMed: 25752740
Affiliations:
- Australie, Belgique, Canada, Danemark, Espagne, France, Royaume-Uni, États-Unis
- Angleterre, Arizona, Bourgogne, Bourgogne-Franche-Comté, Communauté de Madrid, Grand Londres, Hovedstaden, Illinois, Massachusetts, Nouvelle-Galles du Sud, Ontario, Région de Bruxelles-Capitale, Texas
- Bruxelles, Copenhague, Dijon, Londres, Madrid, Sydney, Toronto
- Université de Toronto, Université libre de Bruxelles
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Le document en format XML
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Boyle</name><affiliation wicri:level="3"><nlm:affiliation>Mater Hospital, Sydney, Australia. Electronic address: frances.boyle@sydney.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Mater Hospital, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Smith, Ian E" sort="Smith, Ian E" uniqKey="Smith I" first="Ian E" last="Smith">Ian E. Smith</name><affiliation wicri:level="3"><nlm:affiliation>Royal Marsden Hospital, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Royal Marsden Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="O Shaughnessy, Joyce" sort="O Shaughnessy, Joyce" uniqKey="O Shaughnessy J" first="Joyce" last="O'Shaughnessy">Joyce O'Shaughnessy</name><affiliation wicri:level="2"><nlm:affiliation>Baylor Sammons Cancer Center, Texas Oncology, US Oncology, Dallas, TX, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Baylor Sammons Cancer Center, Texas Oncology, US Oncology, Dallas, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name><affiliation wicri:level="3"><nlm:affiliation>Rigshospitalet, DBCG Secretariat, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Rigshospitalet, DBCG Secretariat, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Buzdar, Aman U" sort="Buzdar, Aman U" uniqKey="Buzdar A" first="Aman U" last="Buzdar">Aman U. Buzdar</name><affiliation wicri:level="2"><nlm:affiliation>UT MD Anderson Cancer Center, Houston, TX, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>UT MD Anderson Cancer Center, Houston, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Fumoleau, Pierre" sort="Fumoleau, Pierre" uniqKey="Fumoleau P" first="Pierre" last="Fumoleau">Pierre Fumoleau</name><affiliation wicri:level="3"><nlm:affiliation>Centre GF Leclerc, Dijon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre GF Leclerc, Dijon</wicri:regionArea><placeName><region type="region">Bourgogne-Franche-Comté</region><region type="old region">Bourgogne</region><settlement type="city">Dijon</settlement></placeName></affiliation></author><author><name sortKey="Gradishar, William" sort="Gradishar, William" uniqKey="Gradishar W" first="William" last="Gradishar">William Gradishar</name><affiliation wicri:level="2"><nlm:affiliation>Northwestern University, Chicago, IL, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Northwestern University, Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Martin, Miguel" sort="Martin, Miguel" uniqKey="Martin M" first="Miguel" last="Martin">Miguel Martin</name><affiliation wicri:level="3"><nlm:affiliation>Hospital Universitario Gregorio Marañón, Universidad Complutense, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital Universitario Gregorio Marañón, Universidad Complutense, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Moy, Beverly" sort="Moy, Beverly" uniqKey="Moy B" first="Beverly" last="Moy">Beverly Moy</name><affiliation wicri:level="2"><nlm:affiliation>Massachusetts General Hospital, Boston, MA, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Massachusetts General Hospital, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Piccart Gebhart, Martine" sort="Piccart Gebhart, Martine" uniqKey="Piccart Gebhart M" first="Martine" last="Piccart-Gebhart">Martine Piccart-Gebhart</name><affiliation wicri:level="4"><nlm:affiliation>Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Institut Jules Bordet, Université Libre de Bruxelles, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region><settlement type="city">Bruxelles</settlement></placeName><orgName type="university">Université libre de Bruxelles</orgName></affiliation></author><author><name sortKey="Pritchard, Kathleen I" sort="Pritchard, Kathleen I" uniqKey="Pritchard K" first="Kathleen I" last="Pritchard">Kathleen I. Pritchard</name><affiliation wicri:level="4"><nlm:affiliation>Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Sunnybrook Odette Cancer Centre, University of Toronto, Toronto</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Lindquist, Deborah" sort="Lindquist, Deborah" uniqKey="Lindquist D" first="Deborah" last="Lindquist">Deborah Lindquist</name><affiliation wicri:level="2"><nlm:affiliation>Arizona Oncology, US Oncology, Sedona, AZ, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Arizona Oncology, US Oncology, Sedona, AZ</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Amonkar, Mayur" sort="Amonkar, Mayur" uniqKey="Amonkar M" first="Mayur" last="Amonkar">Mayur Amonkar</name><affiliation wicri:level="1"><nlm:affiliation>GlaxoSmithKline, Collegeville, PA, United States; GlaxoSmithKline, Uxbridge, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>GlaxoSmithKline, Collegeville, PA, United States; GlaxoSmithKline, Uxbridge</wicri:regionArea><wicri:noRegion>Uxbridge</wicri:noRegion></affiliation></author><author><name sortKey="Huang, Yingjie" sort="Huang, Yingjie" uniqKey="Huang Y" first="Yingjie" last="Huang">Yingjie Huang</name><affiliation wicri:level="1"><nlm:affiliation>GlaxoSmithKline, Collegeville, PA, United States; GlaxoSmithKline, Uxbridge, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>GlaxoSmithKline, Collegeville, PA, United States; GlaxoSmithKline, Uxbridge</wicri:regionArea><wicri:noRegion>Uxbridge</wicri:noRegion></affiliation></author><author><name sortKey="Rappold, Erica" sort="Rappold, Erica" uniqKey="Rappold E" first="Erica" last="Rappold">Erica Rappold</name><affiliation wicri:level="1"><nlm:affiliation>GlaxoSmithKline, Collegeville, PA, United States; GlaxoSmithKline, Uxbridge, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>GlaxoSmithKline, Collegeville, PA, United States; GlaxoSmithKline, Uxbridge</wicri:regionArea><wicri:noRegion>Uxbridge</wicri:noRegion></affiliation></author><author><name sortKey="Williams, Lisa S" sort="Williams, Lisa S" uniqKey="Williams L" first="Lisa S" last="Williams">Lisa S. Williams</name><affiliation wicri:level="1"><nlm:affiliation>GlaxoSmithKline, Collegeville, PA, United States; GlaxoSmithKline, Uxbridge, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>GlaxoSmithKline, Collegeville, PA, United States; GlaxoSmithKline, Uxbridge</wicri:regionArea><wicri:noRegion>Uxbridge</wicri:noRegion></affiliation></author><author><name sortKey="Wang Silvanto, Jing" sort="Wang Silvanto, Jing" uniqKey="Wang Silvanto J" first="Jing" last="Wang-Silvanto">Jing Wang-Silvanto</name><affiliation wicri:level="1"><nlm:affiliation>GlaxoSmithKline, Collegeville, PA, United States; GlaxoSmithKline, Uxbridge, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>GlaxoSmithKline, Collegeville, PA, United States; GlaxoSmithKline, Uxbridge</wicri:regionArea><wicri:noRegion>Uxbridge</wicri:noRegion></affiliation></author><author><name sortKey="Kaneko, Tomomi" sort="Kaneko, Tomomi" uniqKey="Kaneko T" first="Tomomi" last="Kaneko">Tomomi Kaneko</name><affiliation wicri:level="1"><nlm:affiliation>GlaxoSmithKline, Collegeville, PA, United States; GlaxoSmithKline, Uxbridge, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>GlaxoSmithKline, Collegeville, PA, United States; GlaxoSmithKline, Uxbridge</wicri:regionArea><wicri:noRegion>Uxbridge</wicri:noRegion></affiliation></author><author><name sortKey="Finkelstein, Dianne M" sort="Finkelstein, Dianne M" uniqKey="Finkelstein D" first="Dianne M" last="Finkelstein">Dianne M. Finkelstein</name><affiliation wicri:level="2"><nlm:affiliation>Massachusetts General Hospital, Boston, MA, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Massachusetts General Hospital, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Goss, Paul E" sort="Goss, Paul E" uniqKey="Goss P" first="Paul E" last="Goss">Paul E. Goss</name><affiliation wicri:level="2"><nlm:affiliation>Massachusetts General Hospital, Boston, MA, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Massachusetts General Hospital, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author></analytic><series><title level="j">European journal of cancer (Oxford, England : 1990)</title><idno type="eISSN">1879-0852</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antineoplastic Agents (therapeutic use)</term><term>Breast Neoplasms (drug therapy)</term><term>Breast Neoplasms (enzymology)</term><term>Breast Neoplasms (pathology)</term><term>Chemotherapy, Adjuvant</term><term>Disease-Free Survival</term><term>Female</term><term>Humans</term><term>Middle Aged</term><term>Quality of Life</term><term>Quinazolines (therapeutic use)</term><term>Receptor, ErbB-2 (biosynthesis)</term><term>Surveys and Questionnaires</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Antinéoplasiques (usage thérapeutique)</term><term>Enquêtes et questionnaires</term><term>Femelle</term><term>Humains</term><term>Qualité de vie</term><term>Quinazolines (usage thérapeutique)</term><term>Récepteur ErbB-2 (biosynthèse)</term><term>Survie sans rechute</term><term>Traitement médicamenteux adjuvant</term><term>Tumeurs du sein (anatomopathologie)</term><term>Tumeurs du sein (enzymologie)</term><term>Tumeurs du sein (traitement médicamenteux)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Receptor, ErbB-2</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antineoplastic Agents</term><term>Quinazolines</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Tumeurs du sein</term></keywords><keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr"><term>Récepteur ErbB-2</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Breast Neoplasms</term></keywords><keywords scheme="MESH" qualifier="enzymologie" xml:lang="fr"><term>Tumeurs du sein</term></keywords><keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Breast Neoplasms</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Breast Neoplasms</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Tumeurs du sein</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antinéoplasiques</term><term>Quinazolines</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Chemotherapy, Adjuvant</term><term>Disease-Free Survival</term><term>Female</term><term>Humans</term><term>Middle Aged</term><term>Quality of Life</term><term>Surveys and Questionnaires</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Enquêtes et questionnaires</term><term>Femelle</term><term>Humains</term><term>Qualité de vie</term><term>Survie sans rechute</term><term>Traitement médicamenteux adjuvant</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To evaluate health related quality of life (HRQOL) in TEACH, a phase III randomized placebo controlled trial of 12 months of adjuvant lapatinib in HER2 positive (HER2+) early breast cancer which demonstrated marginal benefit in disease-free survival.</div></front></TEI><affiliations><list><country><li>Australie</li><li>Belgique</li><li>Canada</li><li>Danemark</li><li>Espagne</li><li>France</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Arizona</li><li>Bourgogne</li><li>Bourgogne-Franche-Comté</li><li>Communauté de Madrid</li><li>Grand Londres</li><li>Hovedstaden</li><li>Illinois</li><li>Massachusetts</li><li>Nouvelle-Galles du Sud</li><li>Ontario</li><li>Région de Bruxelles-Capitale</li><li>Texas</li></region><settlement><li>Bruxelles</li><li>Copenhague</li><li>Dijon</li><li>Londres</li><li>Madrid</li><li>Sydney</li><li>Toronto</li></settlement><orgName><li>Université de Toronto</li><li>Université libre de Bruxelles</li></orgName></list><tree><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Boyle, Frances M" sort="Boyle, Frances M" uniqKey="Boyle F" first="Frances M" last="Boyle">Frances M. Boyle</name></region></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Smith, Ian E" sort="Smith, Ian E" uniqKey="Smith I" first="Ian E" last="Smith">Ian E. Smith</name></region><name sortKey="Amonkar, Mayur" sort="Amonkar, Mayur" uniqKey="Amonkar M" first="Mayur" last="Amonkar">Mayur Amonkar</name><name sortKey="Huang, Yingjie" sort="Huang, Yingjie" uniqKey="Huang Y" first="Yingjie" last="Huang">Yingjie Huang</name><name sortKey="Kaneko, Tomomi" sort="Kaneko, Tomomi" uniqKey="Kaneko T" first="Tomomi" last="Kaneko">Tomomi Kaneko</name><name sortKey="Rappold, Erica" sort="Rappold, Erica" uniqKey="Rappold E" first="Erica" last="Rappold">Erica Rappold</name><name sortKey="Wang Silvanto, Jing" sort="Wang Silvanto, Jing" uniqKey="Wang Silvanto J" first="Jing" last="Wang-Silvanto">Jing Wang-Silvanto</name><name sortKey="Williams, Lisa S" sort="Williams, Lisa S" uniqKey="Williams L" first="Lisa S" last="Williams">Lisa S. Williams</name></country><country name="États-Unis"><region name="Texas"><name sortKey="O Shaughnessy, Joyce" sort="O Shaughnessy, Joyce" uniqKey="O Shaughnessy J" first="Joyce" last="O'Shaughnessy">Joyce O'Shaughnessy</name></region><name sortKey="Buzdar, Aman U" sort="Buzdar, Aman U" uniqKey="Buzdar A" first="Aman U" last="Buzdar">Aman U. Buzdar</name><name sortKey="Finkelstein, Dianne M" sort="Finkelstein, Dianne M" uniqKey="Finkelstein D" first="Dianne M" last="Finkelstein">Dianne M. Finkelstein</name><name sortKey="Goss, Paul E" sort="Goss, Paul E" uniqKey="Goss P" first="Paul E" last="Goss">Paul E. Goss</name><name sortKey="Gradishar, William" sort="Gradishar, William" uniqKey="Gradishar W" first="William" last="Gradishar">William Gradishar</name><name sortKey="Lindquist, Deborah" sort="Lindquist, Deborah" uniqKey="Lindquist D" first="Deborah" last="Lindquist">Deborah Lindquist</name><name sortKey="Moy, Beverly" sort="Moy, Beverly" uniqKey="Moy B" first="Beverly" last="Moy">Beverly Moy</name></country><country name="Danemark"><region name="Hovedstaden"><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name></region></country><country name="France"><region name="Bourgogne-Franche-Comté"><name sortKey="Fumoleau, Pierre" sort="Fumoleau, Pierre" uniqKey="Fumoleau P" first="Pierre" last="Fumoleau">Pierre Fumoleau</name></region></country><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Martin, Miguel" sort="Martin, Miguel" uniqKey="Martin M" first="Miguel" last="Martin">Miguel Martin</name></region></country><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Piccart Gebhart, Martine" sort="Piccart Gebhart, Martine" uniqKey="Piccart Gebhart M" first="Martine" last="Piccart-Gebhart">Martine Piccart-Gebhart</name></region></country><country name="Canada"><region name="Ontario"><name sortKey="Pritchard, Kathleen I" sort="Pritchard, Kathleen I" uniqKey="Pritchard K" first="Kathleen I" last="Pritchard">Kathleen I. Pritchard</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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